Teacher: Francesco Ricci
Aims: Knowledge of equilibria in solution. Ability to select and use biosensors
Program: Introduction and basic concepts: biosensors. Electrochemical Enzymatic Biosensors. Sensor and electrode preparation. Optical enzymatic biosensors. Signal processing and readout. DNA-based biosensors. Electrochemical DNA-based Biosensors. Sensor and electrode preparation. Immobilization of DNA probes. Optical DNA-based biosensors. Signal processing and readout. DNA-based nanomachines for sensing applications. DNA-based nanoswitches for diagnostic applications. Antibody-based biosensors. Basic and general concepts of ligand-receptor binding. Practical and commercial examples. External lecture. Project on literature examples. 9. Laboratory project on a case study.